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Serum potassium should be closely observed the first 48 hours and potassium should be administered if necessary

Basic research describes experimental or theoretical work undertaken primarily to acquire new knowledge of the underlying foundations of phenomena and observable facts, without any particular application or use in view. Applied research is also original investigation in service of acquiring new knowledge, but is directed primarily towards a specific, practical aim or objective. Development, meanwhile, involves applying ideas formed from research and turning them into either new products or improvements to existing products

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it is not a dosing recommendation